Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2009 Apr 7;15(13):1641-4.
doi: 10.3748/wjg.15.1641.

Liver transplantation for severe hepatic trauma: experience from a single center

Affiliations
Case Reports

Liver transplantation for severe hepatic trauma: experience from a single center

Spiros G Delis et al. World J Gastroenterol. .

Abstract

Liver transplantation has been reported in the literature as an extreme intervention in cases of severe and complicated hepatic trauma. The main indications for liver transplant in such cases were uncontrollable bleeding and postoperative hepatic insufficiency. We here describe four cases of orthotopic liver transplantation after penetrating or blunt liver trauma. The indications were liver failure, extended liver necrosis, liver gangrene and multiple episodes of gastrointestinal bleeding related to portal hypertension, respectively. One patient died due to postoperative cerebral edema. The other three patients recovered well and remain on immunosuppression. Liver transplantation should be considered as a saving procedure in severe hepatic trauma, when all other treatment modalities fail.

PubMed Disclaimer

References

    1. Asensio JA, Demetriades D, Chahwan S, Gomez H, Hanpeter D, Velmahos G, Murray J, Shoemaker W, Berne TV. Approach to the management of complex hepatic injuries. J Trauma. 2000;48:66–69. - PubMed
    1. Demetriades D, Hadjizacharia P, Constantinou C, Brown C, Inaba K, Rhee P, Salim A. Selective nonoperative management of penetrating abdominal solid organ injuries. Ann Surg. 2006;244:620–628. - PMC - PubMed
    1. Schroeppel TJ, Croce MA. Diagnosis and management of blunt abdominal solid organ injury. Curr Opin Crit Care. 2007;13:399–404. - PubMed
    1. Ringe B, Pichlmayr R, Ziegler H, Grosse H, Kuse E, Oldhafer K, Bornscheuer A, Gubernatis G. Management of severe hepatic trauma by two-stage total hepatectomy and subsequent liver transplantation. Surgery. 1991;109:792–795. - PubMed
    1. Ringe B, Pichlmayr R. Total hepatectomy and liver transplantation: a life-saving procedure in patients with severe hepatic trauma. Br J Surg. 1995;82:837–839. - PubMed

Publication types