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. 2009 Oct;54(5):676-82.
doi: 10.1016/j.toxicon.2009.03.021. Epub 2009 Mar 31.

Basic and clinical aspects of BOTOX

Mitchell F Brin  1
Affiliations

Basic and clinical aspects of BOTOX

Mitchell F Brin. Toxicon. 2009 Oct.

Abstract

BOTOX is a botulinum toxin type A product from Allergan that is approved in more than 70 countries, where it addresses unmet patient needs across a variety of indications. BOTOX is a well-characterized and highly purified biological product that is not interchangeable with any other botulinum neurotoxin. The pharmacology, efficacy and safety profile of BOTOX has been established in numerous preclinical and clinical studies in addition to meta-analyses. BOTOX exhibits a predictable response, with a concomitant low rate of neutralizing antibody formation. Allergan is committed to the development of new indications and novel biologics that are designed to benefit individuals with unmet medical needs.

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