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. 2009 May;10(5):444-8.
doi: 10.1038/embor.2009.61. Epub 2009 Apr 3.

The 30th anniversary of quasispecies. Meeting on 'Quasispecies: past, present and future'

Esteban Domingo  1 , Simon Wain-Hobson
Affiliations

The 30th anniversary of quasispecies. Meeting on 'Quasispecies: past, present and future'

Esteban Domingo et al. EMBO Rep. 2009 May.
No abstract available

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Figures

Figure 1
Figure 1
Schematic of viral quasispecies and fitness variations. Mutant distributions—here, genomes are shown as lines and mutations are depicted as symbols on the lines—can be subjected to large population passages (large arrow on the right) that result in fitness gain. Repeated bottleneck events (small arrows) result in fitness decrease. Based on data reviewed in Domingo et al (2006).
None
Esteban Domingo
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Simon Wain-Hobson
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The meeting on ‘Quasispecies: past, present and future' took place between 17 and 18 November 2008, in Barcelona, Spain, and was organized by J. Gómez, C. López-Galíndez, M.A. Martínez & A. Mas.
See this image and copyright information in PMC

References

    1. Batschelet E, Domingo E, Weissmann C (1976) The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate. Gene 1: 27–32 - PubMed
    1. Cattaneo R, Schmid A, Eschle D, Baczko K, ter Meulen V, Billeter MA (1988) Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell 55: 255–265 - PMC - PubMed
    1. Domingo E, Flavell RA, Weissmann C (1976) In vitro site-directed mutagenesis: generation and properties of an infectious extracistronic mutant of bacteriophage Qβ. Gene 1: 3–25 - PubMed
    1. Domingo E, Sabo D, Taniguchi T, Weissmann C (1978) Nucleotide sequence heterogeneity of an RNA phage population. Cell 13: 735–744 - PubMed
    1. Domingo E, Davila M, Ortin J (1980) Nucleotide sequence heterogeneity of the RNA from a natural population of foot-and-mouth-disease virus. Gene 11: 333–346 - PubMed

Publication types