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Comment
. 2009;10(3):212.
doi: 10.1186/gb-2009-10-3-212. Epub 2009 Mar 27.

The need for speed

Paul Flicek  1
Affiliations
Comment

The need for speed

Paul Flicek. Genome Biol. 2009.

Abstract

DNA sequence data are being produced at an ever-increasing rate. The Bowtie sequence-alignment algorithm uses advanced data structures to help data analysis keep pace with data generation.

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Figures

Box 1. Resequencing and functional studies
Box 1. Resequencing and functional studies
A small sampling of recent work leveraging the developments in DNA sequencing technology.
See this image and copyright information in PMC

Comment on

References

    1. Langmead B, Trapnell C, Pop M, Salzberg SL. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biology. 2009;10:R25. doi: 10.1186/gb-2009-10-3-r25. - DOI - PMC - PubMed
    1. 1000 Genomes http://www.1000genomes.org/page.php
    1. Stein LD. Bioinformatics: alive and kicking. Genome Biol. 2008;9:114. doi: 10.1186/gb-2008-9-12-114. - DOI - PMC - PubMed
    1. bzip2 http://bzip.org
    1. Gräf S, Nielsen FG, Kurtz S, Huynen MA, Birney E, Stunnenberg H, Flicek P. Optimized design and assessment of whole genome tiling arrays. Bioinformatics. 2007;23:i195–i204. doi: 10.1093/bioinformatics/btm200. - DOI - PMC - PubMed

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