Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Jun 5;583(11):1699-702.
doi: 10.1016/j.febslet.2009.03.061. Epub 2009 Apr 2.

The coiled coil-helix-coiled coil-helix proteins may be redox proteins

Lucia Banci  1 , Ivano Bertini, Simone Ciofi-Baffoni, Kostas Tokatlidis
Affiliations
Free article
Review

The coiled coil-helix-coiled coil-helix proteins may be redox proteins

Lucia Banci et al. FEBS Lett. .
Free article

Abstract

A number of nuclear encoded proteins are imported in to the intermembrane space of mitochondria where they adopt a coiled coil-helix-coiled coil-helix (CHCH) fold. Two disulfide bonds formed by twin CX(3)C or CX(9)C motifs stabilize this fold. Some of these proteins are also characterized at their N-termini by the presence of two additional cysteine residues which can perform oxidoreductase or metallochaperone functions or both. This fold represents the most 'minimal' oxidoreductase domain described so far.

PubMed Disclaimer

LinkOut - more resources