Training surface and intensity: inflammation, hemolysis, and hepcidin expression
- PMID: 19346972
- DOI: 10.1249/MSS.0b013e318192ce58
Training surface and intensity: inflammation, hemolysis, and hepcidin expression
Abstract
Purpose: This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running.
Methods: Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75%-80% peak VO2 running velocity, and a 10 x 1-km interval running session (INT) at 90%-95% of the peak VO2 running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression.
Results: After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P < 0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P < 0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P < 0.05) but were not different between trials.
Conclusion: Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.
Similar articles
-
Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity.Eur J Appl Physiol. 2009 May;106(1):51-9. doi: 10.1007/s00421-009-0988-7. Epub 2009 Jan 31. Eur J Appl Physiol. 2009. PMID: 19184087 Clinical Trial.
-
The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels.Eur J Appl Physiol. 2012 May;112(5):1889-98. doi: 10.1007/s00421-011-2156-0. Epub 2011 Sep 16. Eur J Appl Physiol. 2012. PMID: 21922263
-
Foot impact force and intravascular hemolysis during distance running.Int J Sports Med. 1988 Feb;9(1):56-60. doi: 10.1055/s-2007-1024979. Int J Sports Med. 1988. PMID: 3366521 Clinical Trial.
-
Epidemiological, biological and clinical update on exercise-induced hemolysis.Ann Transl Med. 2019 Jun;7(12):270. doi: 10.21037/atm.2019.05.41. Ann Transl Med. 2019. PMID: 31355237 Free PMC article. Review.
-
Haematological effects of running. A brief review.Sports Med. 1990 Jan;9(1):1-6. doi: 10.2165/00007256-199009010-00001. Sports Med. 1990. PMID: 2408115 Review. No abstract available.
Cited by
-
Acute exercise does not induce an acute phase response (APR) in Standardbred trotters.Can J Vet Res. 2014 Apr;78(2):97-102. Can J Vet Res. 2014. PMID: 24688170 Free PMC article.
-
Acute hypoxic exercise does not alter post-exercise iron metabolism in moderately trained endurance athletes.Eur J Appl Physiol. 2014 Oct;114(10):2183-91. doi: 10.1007/s00421-014-2938-2. Epub 2014 Jul 3. Eur J Appl Physiol. 2014. PMID: 24990089
-
Influence of post-exercise hypoxic exposure on hepcidin response in athletes.Eur J Appl Physiol. 2014 May;114(5):951-9. doi: 10.1007/s00421-014-2829-6. Epub 2014 Feb 1. Eur J Appl Physiol. 2014. PMID: 24487960
-
Factors Influencing the Hepcidin Response to Exercise: An Individual Participant Data Meta-analysis.Sports Med. 2023 Oct;53(10):1931-1949. doi: 10.1007/s40279-023-01874-5. Epub 2023 Jun 22. Sports Med. 2023. PMID: 37347443
-
International society of sports nutrition position stand: nutritional concerns of the female athlete.J Int Soc Sports Nutr. 2023 Dec;20(1):2204066. doi: 10.1080/15502783.2023.2204066. J Int Soc Sports Nutr. 2023. PMID: 37221858 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials
Miscellaneous