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. 2009 Apr 15;87(7):953-5.
doi: 10.1097/TP.0b013e31819d415e.

Clinical tolerance 2008

Allan D Kirk  1
Affiliations

Clinical tolerance 2008

Allan D Kirk. Transplantation. .

Abstract

In 2008, three publications highlighted the transition of tolerance from experimental to experiential. These included the first study to both anticipate and reproducibly deliver human leukocyte antigen-disparate allograft survival without continuous immunosuppressive drug administration. The other two highlighted unique episodes of clinical tolerance. The results from these studies are summarized and discussed.

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References

    1. Roussey-Kesler G, Giral M, Moreau A, et al. Clinical operational tolerance after kidney transplantation. Am J Transplant. 2006;6:736–746. - PubMed
    1. Lerut J, Sanchez-Fueyo A. An appraisal of tolerance in liver transplantation. Am J Transplant. 2006;6:1774–1780. - PubMed
    1. Kawai T, Cosimi AB, Spitzer TR, et al. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2008;358:353–361. - PMC - PubMed
    1. Cosimi AB, Sachs DH. Mixed chimerism and transplantation tolerance. transplantation. 2004;77:943–946. - PubMed
    1. Ciancio G, Burke GW, Moon J, et al. Donor bone marrow infusion in deceased and living donor renal transplantation. Yonsei Med J. 2004 Dec 31;45(6):998–1003. - PubMed

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