Comment
doi: 10.1016/j.cmet.2009.03.010.
Something old, something new, something borrowed .
Affiliations
- PMID: 19356711
- DOI: 10.1016/j.cmet.2009.03.010
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Comment
Something old, something new, something borrowed .
Cell Metab.
2009 Apr.
Free article
Abstract
Two mammalian mitochondrial transcription factors (TFB1M and TFB2M) share homology with universally expressed dimethyltransferases that modify conserved adenines in the small ribosomal subunit rRNA. Work in this issue (Metodiev et al., 2009) shows that loss of TFB1M abolishes mitochondrial ribosome assembly without affecting mitochondrial transcription.
Comment on
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Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome.Cell Metab. 2009 Apr;9(4):386-97. doi: 10.1016/j.cmet.2009.03.001. Cell Metab. 2009. PMID: 19356719
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