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. 1977 Apr 15;76(2):237-41.
doi: 10.1016/0009-8981(77)90102-4.

Plasma triglyceride secretion and metabolism in chronic renal failure

D G Cramp, T R Tickner, D J Beale, J F Moorhead, M R Wills

Plasma triglyceride secretion and metabolism in chronic renal failure

D G Cramp et al. Clin Chim Acta. .

Abstract

Endogenous very low density lipoprotein triglyceride (VLDL-TG) production rate has been studied in 13 patients with chronic renal failure who were not on dialysis treatment. In these patients the VLDL-TG plasma concentration was significanlty raised when compared with the control group; the fractional turnover rate was reduced but the absolute turnover rate was increased. The results suggest that increased hepatic production of VLDL-TG is a contributory factor to the hypertriglyceridaemia of chronic renal failure.

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