Review
[Change of cartilage matrix metabolism under stress]
[Article in
Chinese]
Affiliations
- PMID: 19366125
Item in Clipboard
Review
[Change of cartilage matrix metabolism under stress]
[Article in
Chinese]
Zhongguo Gu Shang.
2009 Mar.
Abstract
With the effects of the mechanics and biological factors, the imbalance between the degradation and synthesis of chondrocyte, extracelluar matrix and subchondral bone leads to the osteoarthritis. The imbalance between MMPs and TIMPs caused by biomechanical abnormality is the key factor of osteoarthritis. This review will focus on the stress and their roles in the metabolism of the cartilage matrix.
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