Multiple target regulation by small noncoding RNAs rewires gene expression at the post-transcriptional level
- PMID: 19366629
- DOI: 10.1016/j.resmic.2009.03.004
Multiple target regulation by small noncoding RNAs rewires gene expression at the post-transcriptional level
Abstract
Small noncoding RNAs (sRNAs), often in conjunction with Hfq protein, have increasingly been shown to regulate multiple rather than individual mRNAs, thereby reprogramming gene expression at the post-transcriptional level. This review summarizes how and when several such regulators (CyaR, DsrA, GcvB, OmrAB, RNAIII, RybB, RyhB) act upon multiple targets.
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