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Comment
. 2009 May;75(9):873-4.
doi: 10.1038/ki.2009.46.

Is hepcidin the star player in iron metabolism in chronic kidney disease?

Yasuhiro Hamada  1 , Masafumi Fukagawa
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Is hepcidin the star player in iron metabolism in chronic kidney disease?

Yasuhiro Hamada et al. Kidney Int. 2009 May.
Free article

Abstract

It is well known that abnormal iron metabolism contributes to the development of anemia in chronic kidney disease (CKD) patients. Hepcidin is a circulating peptide produced in the liver that regulates efflux of iron from the cells. Ashby et al. measured the serum level of hepcidin using a new assay. Although the new assay produced mixed results and needs to be verified, these data suggest that hepcidin is not the only star player in iron metabolism in CKD.

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