A s-myly route toward lymphoid differentiation
- PMID: 19371711
- DOI: 10.1016/j.immuni.2009.03.006
A s-myly route toward lymphoid differentiation
Abstract
In this issue of Immunity, Ng et al. (2009) show that lymphoid-lineage priming occurs in hematopoietic stem cells and is dependent on the Ikaros transcription factor, as is repression of self-renewal genes during lymphoid differentiation.
Comment on
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Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells.Immunity. 2009 Apr 17;30(4):493-507. doi: 10.1016/j.immuni.2009.01.014. Epub 2009 Apr 2. Immunity. 2009. PMID: 19345118 Free PMC article.
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