Fighting the flu with inflammasome signaling
- PMID: 19371712
- DOI: 10.1016/j.immuni.2009.03.011
Fighting the flu with inflammasome signaling
Abstract
A wide variety of stimuli induce the inflammasome, but little is known about its role in immune protection against viruses. In this issue of Immunity, Allen et al. (2009) and Thomas et al. (2009) describe a critical role for NLRP3 induction of the inflammasome and protection against influenza virus infection.
Comment on
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The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.Immunity. 2009 Apr 17;30(4):556-65. doi: 10.1016/j.immuni.2009.02.005. Epub 2009 Apr 9. Immunity. 2009. PMID: 19362020 Free PMC article.
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