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Comparative Study
. 1991 Mar-Apr;76(2):135-40.

Infections in haematologic neoplasms: autopsy findings

A Nosari  1 , M Barberis, G Landonio, P Magnani, M Majno, P Oreste, P Sozzi
Affiliations
  • PMID: 1937172
Comparative Study

Infections in haematologic neoplasms: autopsy findings

A Nosari et al. Haematologica. 1991 Mar-Apr.

Abstract

Background and methods: Infections are the main cause of death in most haematologic malignancies. We studied 95 autopsies of patients who died from haematologic neoplasms in the period 1980-1989 at Niguarda Cà Granda Hospital.

Results and conclusions: Infections were the cause of death in 63% of patients. In this group of patients bacterial infections accounted for 43% of deaths; fungal infections were frequent too (28%), mainly among leukemic patients; viral (9%), mycobacterial (7%) and polymicrobic infections (11%) were also documented. Haemorrhages were less frequently fatal (12%) due to the availability of haemocomponents. A high number of fatal haemorrhages were associated with fungal infections. Neoplastic progression was the real cause of death in only a few cases, and cardiovascular and pulmonary complications were fatal in the great majority of the other patients.

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