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Comment
. 2009 May 12;180(10):998-1000.
doi: 10.1503/cmaj.082007. Epub 2009 Apr 16.

What kind of randomized trials do we need?

Merrick Zwarenstein  1 , Shaun Treweek
Affiliations
Comment

What kind of randomized trials do we need?

Merrick Zwarenstein et al. CMAJ. .
No abstract available

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References

    1. Schwartz D, Lellouch J. Explanatory and pragmatic attitudes in therapeutical trials. J Chronic Dis. 1967;20:637–48. [Reprinted in J Clin Epidemiol 2009;62:499–505.] - PubMed
    1. Vallvé C. A critical review of the pragmatic clinical trial [Spanish] Med Clin (Barc) 2003;27:384–8. - PubMed
    1. Fox W, Hill A. Streptomycin treatment of pulmonary tuberculosis. BMJ. 1948;2:769–82. - PMC - PubMed
    1. A brief history of the Center for Drug Evaluation and Research. Rockville (MD): Center for Drug Evaluation and Research, US Food and Drug Administration; 1997. [(accessed 2009 Feb. 12)]. p. 32. Available: www.fda.gov/cder/about/history/Page32.htm.
    1. Investigational new drug application. Code of federal regulations. [(accessed 2009 Feb. 12)]. Title 21, Pt 312 (revised 2008 Apr. 1). Available: www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRsearch.cfm?CFRPart=312.