Magic bullets and surrogate biomarkers circa 2009
- PMID: 19373047
- PMCID: PMC4010118
- DOI: 10.1097/CCM.0b013e3181a09440
Magic bullets and surrogate biomarkers circa 2009
Conflict of interest statement
The authors have not disclosed any potential conflicts of interest.
Comment on
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Stratification is the key: inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis.Crit Care Med. 2009 May;37(5):1567-73. doi: 10.1097/CCM.0b013e31819df06b. Crit Care Med. 2009. PMID: 19325479 Free PMC article.
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References
-
- Tracey KJ, Fong Y, Hesse DG, et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature. 1987;330:662– 664. - PubMed
-
- Beutler B, Milsark IW, Cerami AC. Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science. 1985;229:869– 871. - PubMed
-
- Natanson C, Esposito CJ, Banks SM. The sirens’ songs of confirmatory sepsis trials: Selection bias and sampling error. Crit Care Med. 1998;26:1927–1931. - PubMed
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