Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Oct;17(10):1821-9.
doi: 10.1038/oby.2009.107. Epub 2009 Apr 16.

The endocannabinoid system: potential for reducing cardiometabolic risk

Henry N Ginsberg  1 , Stephen C Woods
Affiliations
Review

The endocannabinoid system: potential for reducing cardiometabolic risk

Henry N Ginsberg et al. Obesity (Silver Spring). 2009 Oct.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Cannabinoid receptor type 1 (CB1) receptor knockout mice sustain a reduced body weight vs. pair-fed wild-type mice. Each data point represents the mean ± s.e.m. of six mice for each group. P < 0.005 for CB1 receptor knockout mice vs. wild-type mice at each data point. P < 0.005 for CB1 receptor knockout mice vs. pair-fed wild-type mice at each data point. Adapted from Cota et al. (41).
Figure 2
Figure 2
Rimonabant in Obesity (RIO) study: placebo-subtracted changes in atherogenic plasma lipoproteins. Data from the intent-to-treat population, last observation carried forward. From Pi-Sunyer et al. (78); Després et al. (79); Scheen et al. (80); Van Gaal et al. (81). HDL-C, high-density lipoprotein-cholesterol.
See this image and copyright information in PMC

References

    1. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults—The Evidence Report. National Institutes of Health. National Institutes of Health. Obes Res. 1998;6(Suppl 2):51S–209S. - PubMed
    1. Leibel RL, Rosenbaum M, Hirsch J. Changes in energy expenditure resulting from altered body weight. N Engl J Med. 1995;332:621–628. - PubMed
    1. Rosenbaum M, Vandenborne K, Goldsmith R, et al. Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects. Am J Physiol Regul Integr Comp Physiol. 2003;285:R183–R192. - PubMed
    1. Gong Y, Ishida-Takahashi R, Villanueva EC, et al. The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms. J Biol Chem. 2007;282:31019–31027. - PubMed
    1. Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW. Central nervous system control of food intake and body weight. Nature. 2006;443:289–295. - PubMed

Publication types