Effects of the application of Aloe vera (L.) and microcurrent on the healing of wounds surgically induced in Wistar rats
- PMID: 19377785
- DOI: 10.1590/s0102-86502009000200013
Effects of the application of Aloe vera (L.) and microcurrent on the healing of wounds surgically induced in Wistar rats
Abstract
Purpose: To investigate the effects of topical application of an Aloe vera gel combined or not with microcurrent application on the healing of skin wounds surgically induced in Wistar rats.
Methods: The animals were randomly divided into the following groups: control group, animals topically treated with Aloe vera, animals treated with a microcurrent, and animals receiving topical application of Aloe vera combined with microcurrent application.
Results: The results indicated differences in wound healing between the various treatments when compared to the control group. Tissue hyperplasia was lower in the control group compared to the other treated groups. Accelerated wound healing was observed in the group treated with Aloe vera compared to control. Animals submitted to microcurrent application only and the group treated with microcurrent plus Aloe vera presented an earlier onset of the proliferative phase compared to the control group and animals treated with Aloe vera gel alone. Morphometric data confirmed the structural findings.
Conclusion: Simultaneous application of Aloe vera gel and microcurrent is an excellent choice for the treatment of open wounds thus indicating a synergistic action of these two applications.
Similar articles
-
Topical Application of Aloe vera Accelerated Wound Healing, Modeling, and Remodeling: An Experimental Study.Ann Plast Surg. 2016 Jan;77(1):37-46. doi: 10.1097/SAP.0000000000000239. Ann Plast Surg. 2016. PMID: 25003428
-
Effects of microcurrent application alone or in combination with topical Hypericum perforatum L. and Arnica montana L. on surgically induced wound healing in Wistar rats.Homeopathy. 2012 Jul;101(3):147-53. doi: 10.1016/j.homp.2012.05.006. Homeopathy. 2012. PMID: 22818231
-
Application of Jatropha curcas L. seed oil (Euphorbiaceae) and microcurrent on the healing of experimental wounds in Wistar rats.Acta Cir Bras. 2012 Jul;27(7):441-7. doi: 10.1590/s0102-86502012000700002. Acta Cir Bras. 2012. PMID: 22760827
-
Topical Aloe Vera Gel for Accelerated Wound Healing of Split-Thickness Skin Graft Donor Sites: A Double-Blind, Randomized, Controlled Trial and Systematic Review.Plast Reconstr Surg. 2018 Jul;142(1):217-226. doi: 10.1097/PRS.0000000000004515. Plast Reconstr Surg. 2018. PMID: 29649056 Clinical Trial.
-
The Review on Properties of Aloe Vera in Healing of Cutaneous Wounds.Biomed Res Int. 2015;2015:714216. doi: 10.1155/2015/714216. Epub 2015 May 19. Biomed Res Int. 2015. PMID: 26090436 Free PMC article. Review.
Cited by
-
Advancing Chronic Wound Healing through Electrical Stimulation and Adipose-Derived Stem Cells.Adv Healthc Mater. 2025 Apr;14(10):e2403777. doi: 10.1002/adhm.202403777. Epub 2025 Mar 3. Adv Healthc Mater. 2025. PMID: 40025921 Free PMC article. Review.
-
TNF-alpha expression, evaluation of collagen, and TUNEL of Matricaria recutita L. extract and triamcinolone on oral ulcer in diabetic rats.J Appl Oral Sci. 2016 May-Jun;24(3):278-90. doi: 10.1590/1678-775720150481. J Appl Oral Sci. 2016. PMID: 27383710 Free PMC article.
-
Wound Healing Activity of a Traditionally Used Poly Herbal Product in a Burn Wound Model in Rats.Iran Red Crescent Med J. 2015 Sep 22;17(9):e19960. doi: 10.5812/ircmj.19960. eCollection 2015 Sep. Iran Red Crescent Med J. 2015. PMID: 26473072 Free PMC article.
-
Influence of microcurrent on the modulation of remodelling genes in a wound healing assay.Mol Biol Rep. 2021 Feb;48(2):1233-1241. doi: 10.1007/s11033-021-06135-0. Epub 2021 Jan 21. Mol Biol Rep. 2021. PMID: 33475929
-
A topical ointment formulation containing leaves' powder of Lawsonia inermis accelerate excision wound healing in Wistar rats.Vet World. 2020 Jul;13(7):1280-1287. doi: 10.14202/vetworld.2020.1280-1287. Epub 2020 Jul 7. Vet World. 2020. PMID: 32848301 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical