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. 2009 May 21;11(10):2197-200.
doi: 10.1021/ol900541n.

CuBr-catalyzed oxidative difluoromethylation of tertiary amines with difluoroenol silyl ethers

Lingling Chu  1 , Xingang Zhang, Feng-Ling Qing
Affiliations

CuBr-catalyzed oxidative difluoromethylation of tertiary amines with difluoroenol silyl ethers

Lingling Chu et al. Org Lett. .

Abstract

CuBr-catalyzed oxidative difluoromethylation of readily available tertiary amines with difluoroenol silyl ethers was performed under mild conditions to afford beta-amine-alpha,alpha-difluoro ketones.

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