The nucleus inside out--through a rod darkly
- PMID: 19379685
- DOI: 10.1016/j.cell.2009.04.006
The nucleus inside out--through a rod darkly
Abstract
In the nuclei of eukaryotic cells, euchromatin is located at the center, whereas heterochromatin is found at the periphery and is interspersed in the nucleoplasm. Solovei et al. (2009) now reveal that this normal pattern is reversed in the retinal rod cells of mice. This inversion might serve to maximize light transmission to photoreceptors in nocturnal mammals.
Comment on
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Nuclear architecture of rod photoreceptor cells adapts to vision in mammalian evolution.Cell. 2009 Apr 17;137(2):356-68. doi: 10.1016/j.cell.2009.01.052. Cell. 2009. PMID: 19379699
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