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Comment
. 2009 Apr 23;5(4):315-7.
doi: 10.1016/j.chom.2009.03.009.

All for one and one for all: herpesviral microRNAs close in on their prey

Lars Dölken  1 , Stipan Jonjic
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All for one and one for all: herpesviral microRNAs close in on their prey

Lars Dölken et al. Cell Host Microbe. .
Free article

Abstract

Herpesviruses subvert immune cell activation by inhibiting NK cell receptor (NKG2D)-activating ligands such as MICB. A human cytomegalovirus microRNA was recently shown to repress MICB expression. Nachmani et al. (2009) extend this finding to two other human herpesviruses, providing evidence for a conserved functional role of viral microRNAs despite no sequence conservation among them.

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