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Comment
. 2009 May;5(5):247-9.
doi: 10.1038/nrneph.2009.51.

Vasculitis syndromes: LAMP-2 illuminates pathogenesis of ANCA glomerulonephritis

Xavier Bosch  1 , Eduard Mirapeix
Affiliations
Comment

Vasculitis syndromes: LAMP-2 illuminates pathogenesis of ANCA glomerulonephritis

Xavier Bosch et al. Nat Rev Nephrol. 2009 May.

Abstract

The discovery that antibodies to a bacterial antigen can cross-react with a mammalian protein to cause pauci-immune necrotizing and crescentic glomerulonephritis opens up new possibilities for the diagnosis and treatment of this condition.

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Comment on

  • Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis.
    Kain R, Exner M, Brandes R, Ziebermayr R, Cunningham D, Alderson CA, Davidovits A, Raab I, Jahn R, Ashour O, Spitzauer S, Sunder-Plassmann G, Fukuda M, Klemm P, Rees AJ, Kerjaschki D. Kain R, et al. Nat Med. 2008 Oct;14(10):1088-96. doi: 10.1038/nm.1874. Epub 2008 Oct 5. Nat Med. 2008. PMID: 18836458 Free PMC article.

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