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Comment
. 2009 May;5(5):254-6.
doi: 10.1038/nrneph.2009.52.

Vasculitis syndromes: which maintenance therapy for ANCA vasculitis?

Patrick H Nachman  1
Affiliations
Comment

Vasculitis syndromes: which maintenance therapy for ANCA vasculitis?

Patrick H Nachman. Nat Rev Nephrol. 2009 May.

Abstract

Antineutrophil cytoplasmic antibody-associated vasculitides are usually treated with a combination of high-dose corticosteroids and cyclophosphamide therapy to induce remission, commonly followed by maintenance treatment with a less-toxic immunosuppressant. Azathioprine and methotrexate are both options for maintenance therapy, but whether one of these immunosuppressants is superior to the other is unclear.

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Comment on

  • Azathioprine or methotrexate maintenance for ANCA-associated vasculitis.
    Pagnoux C, Mahr A, Hamidou MA, Boffa JJ, Ruivard M, Ducroix JP, Kyndt X, Lifermann F, Papo T, Lambert M, Le Noach J, Khellaf M, Merrien D, Puéchal X, Vinzio S, Cohen P, Mouthon L, Cordier JF, Guillevin L; French Vasculitis Study Group. Pagnoux C, et al. N Engl J Med. 2008 Dec 25;359(26):2790-803. doi: 10.1056/NEJMoa0802311. N Engl J Med. 2008. PMID: 19109574 Clinical Trial.

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