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Review
. 2009 May;10(7):1203-11.
doi: 10.1517/14656560902911488.

Treatment of HIV infection with raltegravir

Lisa M Chirch  1 , Sidonie Morrison, Roy T Steigbigel
Affiliations
Review

Treatment of HIV infection with raltegravir

Lisa M Chirch et al. Expert Opin Pharmacother. 2009 May.

Abstract

Background: Raltegravir, an inhibitor of the HIV-1 integrase enzyme, is now available for the treatment of drug-resistant virus.

Objective: To establish raltegravir as an effective addition to the existing antiretroviral armamentarium by reviewing pharmacokinetics, efficacy, safety and tolerability.

Methods: Data from pharmacokinetic, Phase II and III clinical trials were reviewed.

Results/conclusions: Results from clinical trials indicate that raltegravir is safe and highly effective in the treatment of both antiretroviral-naïve and -experienced patients.

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