SAT in silence
- PMID: 19386254
- DOI: 10.1016/j.devcel.2009.03.013
SAT in silence
Abstract
X chromosome inactivation triggered by Xist RNA can only occur in specific developmental contexts. In this issue of Developmental Cell, Agrelo et al. show that the nuclear matrix protein SATB1 is a critical determinant of Xist responsiveness.
Comment on
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SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells.Dev Cell. 2009 Apr;16(4):507-16. doi: 10.1016/j.devcel.2009.03.006. Dev Cell. 2009. PMID: 19386260 Free PMC article.
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