Hematology: Lenalidomide plus dexamethasone is effective in multiple myeloma
- PMID: 19390545
- DOI: 10.1038/nrclinonc.2009.50
Hematology: Lenalidomide plus dexamethasone is effective in multiple myeloma
Abstract
A prospective subgroup analysis of two prospective, randomized, double-blind, placebo-controlled phase III clinical trials showed that the combination of lenalidomide plus dexamethasone is superior to dexamethasone alone in patients with relapsed or refractory multiple myeloma who had been previously treated with thalidomide; the implications for clinical practice are discussed.
Comment on
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Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure.Blood. 2008 Dec 1;112(12):4445-51. doi: 10.1182/blood-2008-02-141614. Epub 2008 Sep 17. Blood. 2008. PMID: 18799726
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