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Comment
. 2009 May;6(5):256-8.
doi: 10.1038/nrclinonc.2009.42.

Immunotherapy: Vaccine trials in melanoma -- time for reflection

Alexander M M Eggermont  1
Affiliations
Comment

Immunotherapy: Vaccine trials in melanoma -- time for reflection

Alexander M M Eggermont. Nat Rev Clin Oncol. 2009 May.

Abstract

The disappointing results of the large, randomized, controlled trials showing no benefit of vaccines in patients with advanced and metastatic melanoma call for a reassessment of the development of therapeutic vaccines and the importance of better immune monitoring methodology, such as adoptive T-cell therapy with lymphodepletion.

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