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. 2009 Apr;5(4):e1000347.
doi: 10.1371/journal.ppat.1000347. Epub 2009 Apr 24.

Are viruses inhibited by APOBEC3 molecules from their host species?

Susan R Ross  1
Affiliations

Are viruses inhibited by APOBEC3 molecules from their host species?

Susan R Ross. PLoS Pathog. 2009 Apr.
No abstract available

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Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Figure 1
Figure 1. Polymorphisms in APOBEC 3 Genes.
(A) Different splice variants and polymorphic exons found in different inbred mouse strains. Blue boxes denote exons found in inbred strains such as BALB/c and 129; red boxes denote exons with polymorphic amino acid differences in C57BL-derived strains. The table denotes the relative expression levels of the different splice variants expressed in the different strains, as well as the susceptibility (S) or resistance (R) to F-MLV infection. Data taken from references ,,,. (B) Different A3 alleles found in human populations. At least seven SNP polymorphisms have been found in the A3G genes in humans, although only one polymorphic A3G allele, H186R, has been associated with increased susceptibility to HIV-1-mediated disease . Also shown is the presumed recombination event leading to the deletion of part of A3B in some individuals and a fused hA3A/3B gene .
See this image and copyright information in PMC

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