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Meta-Analysis
. 2009 Jul;201(1):107.e1-6.
doi: 10.1016/j.ajog.2009.03.021. Epub 2009 Apr 26.

Diagnostic accuracy of transvaginal sonography for the diagnosis of adenomyosis: systematic review and metaanalysis

Susanna M Meredith  1 , Luis Sanchez-Ramos, Andrew M Kaunitz
Affiliations
Meta-Analysis

Diagnostic accuracy of transvaginal sonography for the diagnosis of adenomyosis: systematic review and metaanalysis

Susanna M Meredith et al. Am J Obstet Gynecol. 2009 Jul.

Abstract

Objective: The purpose of this study was to critically appraise the diagnostic accuracy of transvaginal sonography for diagnosing adenomyosis.

Study design: Computerized databases were used to identify relevant reports published between 1966 and 2007 reporting data on the accuracy of transvaginal sonography for diagnosing adenomyosis in women having hysterectomy. The presence or absence of adenomyosis was confirmed by histopathologic analysis of hysterectomy specimens. The total analysis included 14 trials with 1895 aggregate participants. Two authors independently assessed methodological quality and constructed tables for the assessment of diagnostic measures.

Results: Transvaginal ultrasound predicted adenomyosis with a likelihood ratio of 4.67 (95% confidence interval [CI], 3.13-6.17). The overall prevalence of adenomyosis was 27.9% (95% CI, 25.5-30.3). The probability of adenomyosis with an abnormal transvaginal ultrasound was 66.2% (95% CI, 61.6- 70.6). The probability of adenomyosis with a normal transvaginal ultrasound was 9.1% (95% CI, 7.3-11.1).

Conclusion: Transvaginal sonography appears to be an accurate diagnostic test for adenomyosis.

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