VARNA: Interactive drawing and editing of the RNA secondary structure
- PMID: 19398448
- PMCID: PMC2712331
- DOI: 10.1093/bioinformatics/btp250
VARNA: Interactive drawing and editing of the RNA secondary structure
Abstract
Description: VARNA is a tool for the automated drawing, visualization and annotation of the secondary structure of RNA, designed as a companion software for web servers and databases.
Features: VARNA implements four drawing algorithms, supports input/output using the classic formats dbn, ct, bpseq and RNAML and exports the drawing as five picture formats, either pixel-based (JPEG, PNG) or vector-based (SVG, EPS and XFIG). It also allows manual modification and structural annotation of the resulting drawing using either an interactive point and click approach, within a web server or through command-line arguments.
Availability: VARNA is a free software, released under the terms of the GPLv3.0 license and available at http://varna.lri.fr.
Supplementary information: Supplementary data are available at Bioinformatics online.
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References
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- Blin G, et al. Alignment of RNA structures. IEEE/ACM Trans. Comput. Biol. Bioinform. 2008 [Epub ahead of print, doi: 10.1109/TCBB.2008.28, February 15, 2008] - PubMed
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- Bruccoleri RE, Heinrich G. An improved algorithm for nucleic acid secondary structure display. Comput. Appl. Biosci. 1988;4:167–173. - PubMed
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