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Review
. 2009 Apr;52(2):153-7.

Pharmacological management of postoperative ileus

Farhad Zeinali  1 , Jonah J Stulberg, Conor P Delaney
Affiliations
Review

Pharmacological management of postoperative ileus

Farhad Zeinali et al. Can J Surg. 2009 Apr.

Abstract
in English, French

The duration of postoperative ileus following abdominal surgery is quite variable, and prolonged postoperative ileus is an iatrogenic phenomenon with important influence on patient morbidity, hospital costs and length of stay in hospital. Adequate treatment for prolonged postoperative ileus is important to improve patient morbidity and clinical efficiency. Both clinical and pharmacological management strategies have improved rapidly over the last decade, and appropriate and timely management using multimodal techniques should be used for optimal care. In this review, we define postoperative ileus, describe the pathogenesis and briefly discuss clinical management before detailing potential pharmacologic management options.

La durée de l'iléus postopératoire consécutif à une chirurgie abdominale est assez variable, et l'iléus postopératoire prolongé est un phénomène iatrogène susceptible d'exercer un impact important sur la morbidité, de même que sur les coûts et la durée du séjour hospitalier. Il est important de traiter adéquatement l'iléus postopératoire prolongé afin de réduire la morbidité et d'améliorer l'efficacité clinique. Les stratégies de prise en charge, tant cliniques que pharmacologiques, se sont rapidement améliorées depuis une dizaine d'années; une prise en charge appropriée et précoce faisant appel à des techniques multimodales s'impose pour la prestation de soins optimaux. Dans la présente synthèse, nous définissons l'iléus postopératoire et nous en décrivons brièvement la pathogenèse et le traitement, avant d'aborder plus en détail les options pharmacothérapeutiques possibles.

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References

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