Review
Vigabatrin in refractory epilepsy in adults and its application in children
Affiliations
- PMID: 1940120
Item in Clipboard
Review
Vigabatrin in refractory epilepsy in adults and its application in children
J Child Neurol.
1991.
Abstract
Vigabatrin has been studied in adult drug-resistant epilepsy since 1982 in single-blind and double-blind studies followed by long-term, open evaluations. These studies have provided evidence that vigabatrin is a potent and well-tolerated antiepileptic drug and support its potential value in pediatric epilepsy. The lack of any evidence of human neurotoxicity in these patients is also reassuring regarding its use in children.
Similar articles
-
Neuropathologic findings in patients receiving long-term vigabatrin therapy for chronic intractable epilepsy.J Child Neurol. 1991;Suppl 2:S17-24. J Child Neurol. 1991. PMID: 1940119
-
Vigabatrin in childhood epilepsy.J Child Neurol. 1991;Suppl 2:S30-7. J Child Neurol. 1991. PMID: 1940122 Clinical Trial.
-
Vigabatrin in pediatric epilepsy--an open study.J Child Neurol. 1991;Suppl 2:S38-44. J Child Neurol. 1991. PMID: 1940123 Clinical Trial.
-
The role of vigabatrin in the management of infantile epileptic syndromes.Neurology. 1993 Nov;43(11 Suppl 5):S21-3. Neurology. 1993. PMID: 8232983 Review.
-
Gamma-vinyl GABA (vigabatrin): clinical experience in adult and adolescent patients with intractable epilepsy.Epilepsia. 1992;33 Suppl 5:S30-4; discussion S34-5. Epilepsia. 1992. PMID: 1425498 Review.
Cited by
-
Vigabatrin treatment in children.Childs Nerv Syst. 1994 May;10(4):244-8. doi: 10.1007/BF00301162. Childs Nerv Syst. 1994. PMID: 7923235 Clinical Trial.