Reliability of the Vitek 2 yeast susceptibility test for detection of in vitro resistance to fluconazole and voriconazole in clinical isolates of Candida albicans and Candida glabrata
- PMID: 19403774
- PMCID: PMC2691097
- DOI: 10.1128/JCM.02070-08
Reliability of the Vitek 2 yeast susceptibility test for detection of in vitro resistance to fluconazole and voriconazole in clinical isolates of Candida albicans and Candida glabrata
Abstract
The Vitek 2 yeast susceptibility test was evaluated by testing 122 Candida isolates against fluconazole and voriconazole. Excellent categorical agreement with the CLSI broth microdilution method was observed (97.5% for both the azoles). Moreover, the Vitek 2 system was able to identify all but 2 of 59 investigated fluconazole-resistant organisms.
References
-
- Alexander, B. D., T. C. Byrne, K. L. Smith, K. E. Hanson, K. J. Anstrom, J. R. Perfect, and L. B. Reller. 2007. Comparative evaluation of Etest and Sensititre Yeastone panels against the Clinical and Laboratory Standards Institute M27-A2 reference broth microdilution method for testing Candida susceptibility to seven antifungal agents. J. Clin. Microbiol. 45698-706. - PMC - PubMed
-
- Angiolella, L., A. R. Stringaro, F. De Bernardis, B. Posteraro, M. Bonito, L. Toccacieli, A. Torosantucci, M. Colone, M. Sanguinetti, A. Cassone, and A. T. Palamara. 2008. Increase of virulence and its phenotypic traits in drug-resistant strains of Candida albicans. Antimicrob. Agents Chemother. 52:927-936. - PMC - PubMed
-
- Arthington-Skaggs, B. A., W. Lee-Yong, M. A. Ciblak, J. P. Frade, M. E. Brandt, R. A. Hajjeh, L. E. Harrison, A. N. Sofair, and D. W. Warnock. 2002. Comparison of visual and spectrophotometric methods of broth microdilution MIC endpoint determination and evaluation of sterol quantitation method for in vitro susceptibility testing of fluconazole and itraconazole against trailing and non-trailing Candida isolates. Antimicrob. Agents Chemother. 462477-2481. - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
