Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2009 May;94(5):615-7.
doi: 10.3324/haematol.2009.005769.

Factor IX and deep vein thrombosis

Editorial

Factor IX and deep vein thrombosis

Gordon Lowe. Haematologica. 2009 May.

Abstract

Elevated levels of several coagulation factors have been found to be associated with an increased risk of thrombosis. In this perspective article, Dr. Lowe examines the implications of the report by Bezemer and coworkers in this issue for our understanding of the mechanisms involved and how they should direct future research.

PubMed Disclaimer

Comment on

  • F9 Malmö, factor IX and deep vein thrombosis.
    Bezemer ID, Arellano AR, Tong CH, Rowland CM, Ireland HA, Bauer KA, Catanese J, Reitsma PH, Doggen CJ, Devlin JJ, Rosendaal FR, Bare LA. Bezemer ID, et al. Haematologica. 2009 May;94(5):693-9. doi: 10.3324/haematol.2008.003020. Epub 2009 Mar 13. Haematologica. 2009. PMID: 19286883 Free PMC article.

References

    1. Macfarlane RG. Introduction. Br Med Bull. 1977;33:183–5.
    1. Lowe GDO. Can haematological tests predict cardiovascular risk? The 2005 Kettle Lecture. Br J Haematol. 2006;133:232–50. - PubMed
    1. Bertina RM. Elevated clotting factor levels and venous thrombosis. Pathophysiol Haemost Thromb. 2003;33:395–400. - PubMed
    1. Rumley A, Lowe GDO, Sweetnam PM, Yarnell JWG, Ford RP. Factor VIII, von Willebrand factor and the risk of major ischaemic heart disease in the Caerphilly Study. Br J Haematol. 1999;105:110–6. - PubMed
    1. Whincup P, Danesh J, Walker M, Lennon L, Thomson A, Appleby P, et al. Von Willebrand factor and coronary heart disease: prospective study and meta-analysis. Europ Heart J. 2002;23:1764–70. - PubMed