The relationship between trauma and idiopathic torsion dystonia
- PMID: 1940944
- PMCID: PMC1014477
- DOI: 10.1136/jnnp.54.8.713
The relationship between trauma and idiopathic torsion dystonia
Abstract
Generalised, multifocal or segmental idiopathic torsion dystonia (ITD), is caused by an autosomal dominant gene with reduced penetrance in about 85% of cases. Of 104 patients with these types of ITD, 17 (16.4%) gave a history which suggested that dystonic movements had been precipitated or exacerbated by trauma. Eight of these 17 patients had affected relatives. If precipitated, dystonia appeared first in the injured part of the body within days or up to 12 months after the trauma and later became more widespread. Peripheral injuries may influence basal ganglia function and provoke the onset of dystonic movements in individuals who are ITD gene carriers.
Similar articles
-
Phenotypic characterization of DYT13 primary torsion dystonia.Mov Disord. 2004 Feb;19(2):200-6. doi: 10.1002/mds.10634. Mov Disord. 2004. PMID: 14978677
-
[Genetic study of idiopathic torsion dystonia in Russia].Genetika. 1996 Mar;32(3):415-9. Genetika. 1996. PMID: 8723633 Russian.
-
Rhabdomyolysis due to hereditary torsion dystonia.Pediatr Neurol. 1995 Jul;13(1):83-4. doi: 10.1016/0887-8994(95)00111-r. Pediatr Neurol. 1995. PMID: 7575858
-
The genetics of primary torsion dystonia.Hum Genet. 1990 Jan;84(2):107-15. doi: 10.1007/BF00208922. Hum Genet. 1990. PMID: 2404852 Review.
-
Torsion dystonia.Curr Opin Neurol. 1996 Aug;9(4):317-20. doi: 10.1097/00019052-199608000-00014. Curr Opin Neurol. 1996. PMID: 8858192 Review.
Cited by
-
Possible risk factors for primary adult onset dystonia: a case-control investigation by the Italian Movement Disorders Study Group.J Neurol Neurosurg Psychiatry. 1998 Jan;64(1):25-32. doi: 10.1136/jnnp.64.1.25. J Neurol Neurosurg Psychiatry. 1998. PMID: 9436723 Free PMC article.
-
Double Trouble: A Case of DYT-TOR1A Diagnosed in the Postoperative Period.Ann Indian Acad Neurol. 2023 Jul-Aug;26(4):578-580. doi: 10.4103/aian.aian_39_23. Epub 2023 Sep 11. Ann Indian Acad Neurol. 2023. PMID: 37970319 Free PMC article. No abstract available.
-
Cervical dystonia incidence and diagnostic delay in a multiethnic population.Mov Disord. 2020 Mar;35(3):450-456. doi: 10.1002/mds.27927. Epub 2019 Nov 27. Mov Disord. 2020. PMID: 31774238 Free PMC article.
-
Peripherally induced oromandibular dystonia.J Neurol Neurosurg Psychiatry. 1998 Nov;65(5):722-8. doi: 10.1136/jnnp.65.5.722. J Neurol Neurosurg Psychiatry. 1998. PMID: 9810945 Free PMC article.
-
The non-motor syndrome of primary dystonia: clinical and pathophysiological implications.Brain. 2012 Jun;135(Pt 6):1668-81. doi: 10.1093/brain/awr224. Epub 2011 Sep 20. Brain. 2012. PMID: 21933808 Free PMC article. Review.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical