Specifying mouse embryonic germ cells
- PMID: 19410535
- DOI: 10.1016/j.cell.2009.04.016
Specifying mouse embryonic germ cells
Abstract
Male germ cells are induced to form from the epiblast of the mouse embryo by a combination of WNT and bone morphogenetic protein signals. Ohinata et al. (2009) now clarify the steps of mouse germ cell formation and use this genetic insight to direct the specification and differentiation of germline progenitor cells in vitro.
Comment on
-
A signaling principle for the specification of the germ cell lineage in mice.Cell. 2009 May 1;137(3):571-84. doi: 10.1016/j.cell.2009.03.014. Cell. 2009. PMID: 19410550
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Molecular Biology Databases