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Multicenter Study
. 2009 Apr;32(4):483-90.
doi: 10.1093/sleep/32.4.483.

Association between sleep architecture and measures of body composition

Madhu N Rao  1 , Terri Blackwell, Susan Redline, Marcia L Stefanick, Sonia Ancoli-Israel, Katie L Stone; Osteoporotic Fractures in Men (MrOS) Study Group
Affiliations
Multicenter Study

Association between sleep architecture and measures of body composition

Madhu N Rao et al. Sleep. 2009 Apr.

Abstract

Study objectives: To determine whether slow wave sleep (SWS) is inversely associated with body mass index (BMI) and other measures of body composition.

Design: Cross-sectional, observational study.

Setting: Community-based.

Participants: 2745 older men from the MrOS Sleep Study who completed polysomnography.

Interventions: N/A.

Measurements and results: SWS as a percentage of total sleep duration was obtained from in-home, overnight polysomnography. Measures of body composition including BMI, weight, waist circumference and total body fat mass were determined by standard techniques. Other covariates in the analysis were age, race/ethnicity, clinic site, physical activity, respiratory disturbance index (RDI), total sleep time, and sleep efficiency. In the multivariate analysis, there was a significant inverse association between quartiles of SWS and BMI (P-trend = 0.0095). Older men in the lowest quartile of SWS had an average BMI of 27.4 kg/m2, compared to 26.8 for those in the highest quartile of SWS. This association was attenuated in men with RDI > or = 15. Furthermore, participants in the lowest quartile of SWS had a 1.4-fold increased odds for obesity (P = 0.03, 95% CI 1.0, 1.8) compared to those in the highest quartile. A similar inverse association between SWS and waist circumference as well as weight was observed. REM sleep was not associated with measures of body composition.

Conclusions: Independent of sleep duration, percentage time in SWS is inversely associated with BMI and other measures of body composition in this population of older men. Participants in the lowest quartile of SWS (compared to those in the highest quartile) are at increased risk for obesity.

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References

    1. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 2002;288:1723–27. - PubMed
    1. Kripke DF, Simons RN, Garfinkel L, Hammond EC. Short and long sleep and sleeping pills. Is increased mortality associated? Arch Gen Psychiatry. 1979;36:103–16. - PubMed
    1. National Sleep Foundation. Washington DC: National Sleep Foundation; 2005. Sleep in America poll. 2005.
    1. Kripke DF, Garfinkel L, Wingard DL, Klauber MR, Marler MR. Mortality associated with sleep duration and insomnia. Arch Gen Psychiatry. 2002;59:131–6. - PubMed
    1. Taheri S, Lin L, Austin D, Young T, Mignot E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1:e62. - PMC - PubMed

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