Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1991;29(4):263-7.
doi: 10.1080/02681219180000381.

Intrahyphal hyphae in corneal tissue from a case of keratitis due to Lasiodiplodia theobromae

P A Thomas  1 , R G Garrison, T Jansen
Affiliations
Case Reports

Intrahyphal hyphae in corneal tissue from a case of keratitis due to Lasiodiplodia theobromae

P A Thomas et al. J Med Vet Mycol. 1991.

Erratum in

  • J Med Vet Mycol 1992;30(1):87

Abstract

Lasiodiplodia theobromae, a recognized plant pathogen, was isolated in culture from a case of human mycotic keratitis. Chemotherapy with a variety of azoles was unsuccessful and the lesion was removed surgically. Electron microscopy of thin sections of the excised corneal tissue revealed several examples of intrahyphal hyphae, a unique process described previously in in vitro cultures of various zoopathogenic fungi. We believe this to be the first report of the presence of intrahyphal hyphae in parasitized animal or human tissue. The demonstration of this process in vivo is thought to be consistent with the hypothesis that intrahyphal hyphae might represent an attempt by the invading fungus to survive in an otherwise unfavourable environment.

PubMed Disclaimer

Publication types