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Comment
. 2009 Apr 28;106(17):6885-6.
doi: 10.1073/pnas.0902010106. Epub 2009 Apr 22.

Self-organization in the genome

Tom Misteli  1
Affiliations
Comment

Self-organization in the genome

Tom Misteli. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Self-organization in the genome. Functional interactions among chromosomes give rise to chromosome localization patterns. Interactions include association of centromeres (red), clustering of coregulated genes (green), association of a regulatory element and its target genes (yellow), interaction of a genome region with the nuclear envelope (blue) or clusters of rDNA (black) genes. Each interaction constrains the chromosome's motion, and the sum of all interactions ultimately determines the position of a chromosome relative to all others. The interchromosomal interactions may also indirectly determine the position of a chromosome relative to the center/periphery of the nucleus. Nlo, nucleolus.
See this image and copyright information in PMC

Comment on

References

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