doi: 10.1073/pnas.74.5.1807.
Lipid-protein interaction in the phosphatidylcholine exchange protein
- PMID: 194240
- PMCID: PMC431009
- DOI: 10.1073/pnas.74.5.1807
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Lipid-protein interaction in the phosphatidylcholine exchange protein
Proc Natl Acad Sci U S A.
1977 May.
Abstract
Incorporation of 2-acyl spin-labeled lecithin into the phosphatidylcholine protein from bovine liver results in an immobilization of the spin-label at the methyl and the carboxyl terminal end of the acyl chain. The nitroxide group on the protein-bound lecithin molecule is not accessible to ascorbate. This suggests that lecithin is buried in a pocket on the protein, which effectively shields the acyl chains from the medium.
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