[Haematological adverse effects caused by psychiatric drugs]
- PMID: 19424521
[Haematological adverse effects caused by psychiatric drugs]
Abstract
Almost all clases of psychiatric drugs (typical and atypical antipsychotics, antidepressants, mood stabilizers, benzodiazepines) have been reported as possible causes of haematological toxicity. This is a review of the literature in which different clinical situations involving red blood cells, white blood cells, platelets and impaired coagulation are detailed and the drugs more frequently involved are listed. The haematological adverse reactions detailed here include: aplastic anemia, haemolitic anemia, leukopenia, agranulocytosis, leukocytosis, eosinophilia, thrombocytosis, thrombocytopenia, disordered platelet function and impaired coagulation. The haematologic toxicity profile of the drugs more frequently involved: lithium, clozapine, carbamazepine, valproic acid and SSRI antidepressants is mentioned.
Similar articles
-
Blood dyscrasias induced by psychotropic drugs.Pharmacopsychiatry. 2004 Mar;37 Suppl 1:S70-8. doi: 10.1055/s-2004-815513. Pharmacopsychiatry. 2004. PMID: 15052517
-
Haematological toxicity of drugs used in psychiatry.Hum Psychopharmacol. 2008 Jan;23 Suppl 1:27-41. doi: 10.1002/hup.917. Hum Psychopharmacol. 2008. PMID: 18098216 Review.
-
Hematologic side effects of psychotropic drugs.Psychosomatics. 1986 Feb;27(2):119-20,125-7. doi: 10.1016/S0033-3182(86)72722-9. Psychosomatics. 1986. PMID: 2869545 Review. No abstract available.
-
Hematologic side effects of drugs.Ann Clin Lab Sci. 1989 Mar-Apr;19(2):114-21. Ann Clin Lab Sci. 1989. PMID: 2665627 Review.
-
Hematologic side effects of psychotropics.Psychosomatics. 1999 Sep-Oct;40(5):414-21. doi: 10.1016/S0033-3182(99)71206-5. Psychosomatics. 1999. PMID: 10479946 Review.
Cited by
-
Frequency of anemia in chronic psychiatry patients.Neuropsychiatr Dis Treat. 2015 Oct 22;11:2737-41. doi: 10.2147/NDT.S91581. eCollection 2015. Neuropsychiatr Dis Treat. 2015. PMID: 26543367 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical