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Comment
. 2009 May 8;4(5):371-2.
doi: 10.1016/j.stem.2009.04.010.

The neurofibroma cell of origin: SKPs expand the playing field

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The neurofibroma cell of origin: SKPs expand the playing field

Zachary S Morris et al. Cell Stem Cell. .
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Abstract

Mounting evidence suggests that stem/progenitor cells may be the cells of origin for many tumor types. In this issue of Cell Stem Cell, Le et al. (2009) demonstrate that skin-derived precursors (SKPs) can initiate dermal neurofibromas and highlight the importance of the microenvironment in the formation of this complex tumor.

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