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. 2009 Apr-May;74(4-5):483-6.
doi: 10.1016/j.steroids.2009.01.002. Epub 2009 Jan 17.

Biotransformation of methyl cholate by Aspergillus niger

Amal Al-Aboudi  1 , Mohammad Y Mohammad, Salim Haddad, Rawhi Al-Far, M Iqbal Choudhary, Atta-Ur-Rahman
Affiliations

Biotransformation of methyl cholate by Aspergillus niger

Amal Al-Aboudi et al. Steroids. 2009 Apr-May.

Abstract

Biotransformation of methyl cholate using Aspergillus niger was investigated. This led to the isolation of two derivatives: methyl 3alpha,7alpha,12alpha,15beta-tetrahydroxy-5beta-cholan-24-oate identified as a new compound, and a known compound methyl 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate. The structure elucidation of the new compound was achieved using 1D and 2D NMR, MS and X-ray diffraction.

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