Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jun 17;196(4296):1336-9.
doi: 10.1126/science.194310.

Feline oncornavirus-associated cell membrane antigen: expression in transformed nonproducer mink cells

A H Sliski, M Essex, C Meyer, G Todaro

Feline oncornavirus-associated cell membrane antigen: expression in transformed nonproducer mink cells

A H Sliski et al. Science. .

Abstract

The feline oncornavirus-associated cell membrane antigen (FOCMA) is a target for naturally occurring immunity that protects the cat against development of fibrosarcoma and leukemia. Feline sarcoma virus-transformed "nonproducer" mink cells express high levels of FOCMA, but not the major viral structural proteins. Transformation of the same cells by murine sarcoma virus, or infection with feline leukemia virus, which is nontransforming for epithelial or fibroblastic cells, did not induce FOCMA. Thus, FOCMA expression in mind lung cells is specifically associated with transformation by feline sarcoma virus.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources