Preference in random assignment: implications for the interpretation of randomized trials
- PMID: 19434489
- PMCID: PMC2796239
- DOI: 10.1007/s10488-009-0224-0
Preference in random assignment: implications for the interpretation of randomized trials
Abstract
Random assignment to a preferred experimental condition can increase service engagement and enhance outcomes, while assignment to a less-preferred condition can discourage service receipt and limit outcome attainment. We examined randomized trials for one prominent psychiatric rehabilitation intervention, supported employment, to gauge how often assignment preference might have complicated the interpretation of findings. Condition descriptions, and greater early attrition from services-as-usual comparison conditions, suggest that many study enrollees favored assignment to new rapid-job-placement supported employment, but no study took this possibility into account. Reviews of trials in other service fields are needed to determine whether this design problem is widespread.
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References
-
- Abelson RP. Statistics as principled argument. Hillsdale, NJ: Lawrence Erlbaum; 1995.
-
- Aguinis H. Regression analysis for categorical moderators. New York: Guilford Press; 2004.
-
- Aiken LS, West SG. Multiple regression: Testing and interpreting interactions. Newbury Park, CA: Sage; 1991.
-
- Alverson H, Alverson M, Drake RE, Becker DR. Social correlates of competitive employment among people with severe mental illness. Psychosocial Rehabilitation Journal. 1998;22(1):34–40.
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