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Case Reports
. 2009 Jun 15;48(12):1732-5.
doi: 10.1086/599224.

Intravenous tigecycline as adjunctive or alternative therapy for severe refractory Clostridium difficile infection

Affiliations
Case Reports

Intravenous tigecycline as adjunctive or alternative therapy for severe refractory Clostridium difficile infection

Bjorn L Herpers et al. Clin Infect Dis. .

Abstract

Clostridium difficile infection (CDI) has become more refractory to standard therapy. We describe 4 patients with severe refractory CDI who were successfully treated with tigecycline. Symptoms improved within 1 week. No relapses were observed. This favorable outcome suggests that tigecycline might be a useful alternative for treating severe refractory CDI.

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