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Randomized Controlled Trial
. 2009;5(1):45-52.
Epub 2009 Apr 8.

Risk factors associated with methamphetamine use and heart failure among native Hawaiians and other Pacific Island peoples

Marjorie K Mau  1 , Karynna Asao, Jimmy Efird, Erin Saito, Robert Ratner, Muhannad Hafi, Todd Seto
Affiliations
Randomized Controlled Trial

Risk factors associated with methamphetamine use and heart failure among native Hawaiians and other Pacific Island peoples

Marjorie K Mau et al. Vasc Health Risk Manag. 2009.

Abstract

Objective: Heart failure (HF), a long term outcome of chronic methamphetamine use (MU), occurs more frequently in racial and ethnic minority populations at high risk for cardiovascular disparities. This study examined the association of socio-demographic and clinical risk factors with MU among heart failure patients who are Native Hawaiians (NH) or other Pacific Island peoples (PIP). DESIGN/SETTING/PATIENT POPULATION: Cross-sectional study of NHs and PIPs with advanced heart failure enrolled in the Malama Pu'uwai Study, a randomized control trial to test an educational intervention to reduce re-hospitalization and/or death. A total of 82 participants were enrolled between 6/1/06 to 12/31/07 and met the following eligibility criteria: 1) self-identified NH or PIP, 2) Left ventricular systolic ejection fraction <or=45%, 3) Age of 21 years or older. Data were analyzed by odds ratios (OR), 95% confidence intervals (CI), and multiple logistic regression analysis.

Main outcome measure: Methamphetamine use.

Results: Twenty-two percent of HF participants were identified as being current or prior methamphetamine users. Younger age and non-married status (combined never married or divorced/separated) were independently associated with MU after adjustment for sex, education, and other co-morbidities associated with HF (ie, age >50 years, OR = 0.16, 95% CI, 0.03-0.84; non-married status combined as never married OR = 8.5, CI, 1.5-47; divorced/separated OR = 11, CI 1.8-75).

Conclusions: RISK FACTORS ASSOCIATED WITH MU IN NH AND PIPS WITH HEART FAILURE INCLUDE: younger age and being divorced/separated or never married. Health care providers should be aware of MU as a contributing factor in the approach and treatment of HF in NHs and PIPs.

Keywords: Native Hawaiian and other Pacific Islander; ethnic minority; heart failure; methamphetamine use.

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References

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