Hypothesis: pathogenesis of postmenopausal hot flush
- PMID: 1943887
- DOI: 10.1016/0306-9877(91)90282-4
Hypothesis: pathogenesis of postmenopausal hot flush
Abstract
The pathogenesis of postmenopausal hot flush is still poorly understood. A hypothesis is presented where the perimenopausal decline in circulating estrogen levels may increase central norepinephrine and LH-RH secretion and produce a downward setting of the central thermostat resulting in a hot flush.
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