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. 1991 Aug;35(4):349-50.
doi: 10.1016/0306-9877(91)90282-4.

Hypothesis: pathogenesis of postmenopausal hot flush

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Hypothesis: pathogenesis of postmenopausal hot flush

J Rosenberg et al. Med Hypotheses. 1991 Aug.

Abstract

The pathogenesis of postmenopausal hot flush is still poorly understood. A hypothesis is presented where the perimenopausal decline in circulating estrogen levels may increase central norepinephrine and LH-RH secretion and produce a downward setting of the central thermostat resulting in a hot flush.

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