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Case Reports
. 2009 Apr-Jun;21(2):77-80.

3 case reports of edema associated with quetiapine

Hristina K Koleva  1 , Mark A Erickson, Erik R Vanderlip, Janeta Tansey, Joseph Mac, Jess G Fiedorowicz
Affiliations
Case Reports

3 case reports of edema associated with quetiapine

Hristina K Koleva et al. Ann Clin Psychiatry. 2009 Apr-Jun.

Abstract

Background: Edema associated with quetiapine has been described in only one case report to date and represents a potentially serious adverse reaction.

Methods: We present a case series of 3 patients who developed bilateral leg edema following initiation of quetiapine.

Results: One of these patients had a recurrence of edema with subsequent rechallenge. Another patient developed quetiapine-induced edema following a prior episode of olanzapine-induced edema. All 3 cases present a compelling temporal relationship between the drug challenge and the adverse event.

Conclusion: Prompt recognition and intervention with discontinuation of the offending agent is important for this potentially serious, seemingly idiosyncratic vascular complication.

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